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Sub-acute Toxicosis Caused by a Multiple Doses Tegafur/Uracil (UFT) for Suicide : A Case Report
http://hdl.handle.net/10087/3914
http://hdl.handle.net/10087/3914e306edd1-3c33-46f6-95a8-889a59071f70
名前 / ファイル | ライセンス | アクション |
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57_317.pdf (174.3 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-11-10 | |||||
タイトル | ||||||
タイトル | Sub-acute Toxicosis Caused by a Multiple Doses Tegafur/Uracil (UFT) for Suicide : A Case Report | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | tegafur/uracil (UFT) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | toxicosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | suicide attempt | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pancytopenia | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Hagiwara, Shuichi
× Hagiwara, Shuichi× Ogino, Takashi× Takahashi, Yuga× Isaka, Akira× Nameki, Taro× Kagoshima, Kaie× Yamada, Takuro× Ishihara, Kouichi× Hiraishi, Hikaru× Kurabayashi, Kazutaka× Handa, Hiroshi× Iino, Yuichi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Tegafur/uracil (UFT) is an oral anticancer drug composed of tegafur which is a derivative of\nfluorouracil (5-FU) and uracil in a molar ratio of 1:4. UFT is effective as adjuvant chemotherapy for\nbreast cancer2, colorectal cancer3, non-small cell lung carcinoma4, head and neck cancer5 and other\ntumors. We report a 41-year-old man who orally ingested a large dose of UFT (tegafur: 40000 mg/\nuracil 9960mg)in an effort to commit suicide, and suffered from sub-acute toxicosis(main symptoms were\nbone-marrow suppression, and hair loss) of UFT. His life was saved by empiric antibiotic chemical\ntreatment (meropenem, isapamicin, and micafungin), and granulocyte colony-stimulating factor (G\n-CSF). In the case of toxicosis of UFT, strong antibacterial empiric chemotherapy and G-CSF are\nnecessary for rescue. If G-CSF is not work, biopsy of bone marrow woud be necessary, and the case of\nno stem cells, bone marrow transfusion should be thought. | |||||
書誌情報 |
The Kitakanto medical journal = 北関東医学 巻 57, 号 4, p. 317-320, 発行日 2007-11-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1343-2826 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10585677 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 北関東医学会 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article | |||||
更新日 | ||||||
日付 | 2017-03-27 | |||||
日付タイプ | Created |