2026-03-13T08:48:02Z https://gunma-u.repo.nii.ac.jp/oai

oai:gunma-u.repo.nii.ac.jp:00001463 2023-06-19T13:45:57Z 384:385:386:393

リンパ球のプリン代謝(V) : Sarcoma 180担癌マウスの脾細胞のプリンヌクレオシドホスホリラーゼ活性とサプレッサー細胞活性 Purine Metabolic Enzymes in Lymphocytes. V. : Purine Nucleoside Phosphorylase Activity and Suppuressor Cell Activity of Sarcoma 180-bearing Mouse Spleen Cells Akuzawa, Yuki 2214 Yoshida, Toshiharu 2215 Kurashige, Satonori 2216 Sarcoma 180 PNP ADA Suppressor cell application/pdf Departmental Bulletin Paper Purine nucleoside phosphorylase (PNP) activity in spleen lymphocytes of Sarcoma 180-bearing mice increased from early time after S180 transplantation and reached 5 times the normal value within 8 weeks, while no significant change was observed in adenosine deaminase (ADA) activity. More than 5 times and 3 times the normal activity of PNP were found in B and T lymphocytes, respectively, in S180-bearing mice at 8 weeks after the tumor graft. The S180-bearing mouse T and B lymphocytes with high PNP activity showed suppressor activity against the concanavalin A response of normal lymphocytes. These results suggest that PNP activity in tumor-bearing mice may be related to suppressor cell activity. departmental bulletin paper 群馬大学医療技術短期大学部 1987-02-20 2017-03-27 VoR application/pdf 群馬大学医療技術短期大学部紀要 7 217 221 AN00068340 0389-7540 https://gunma-u.repo.nii.ac.jp/record/1463/files/KJ00004436047.pdf http://hdl.handle.net/10087/1904 https://gunma-u.repo.nii.ac.jp/records/1463 eng