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アイテム
Antitumor Effect of Interleukin 2 and Cyclophosphamide Administration
http://hdl.handle.net/10087/1949
http://hdl.handle.net/10087/1949c332b5e5-1e0e-47a9-874f-198be0911dd4
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00004436131.pdf (478.6 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-12-20 | |||||
| タイトル | ||||||
| タイトル | Antitumor Effect of Interleukin 2 and Cyclophosphamide Administration | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| その他のタイトル | ||||||
| その他のタイトル | インターロイキン2及びサイクロホソファミドの抗腫瘍効果 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Interleukin 2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Cyclophosphamide | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Blastogenesis | |||||
| 著者 |
Kurashige, Satonori
× Kurashige, Satonori× Akuzawa, Yuki× Kodama, Kazue |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | EL4-bearing C57BL mice were treated cyclophosphamide and/or with IL2. Mice treated with cyclophosphamide alone survived significantly longer than nontreated mice, while IL2-treated mice did not. Mice treated with both cyclophosphamide and IL2 survived significantly longer than mice treated with cyclophosphamide alone. IL2 response of lymphocytes was markedly depressed in EL4-bearing mice. Lymphocytes from EL4-bearing mice treated with cyclophosphamide alone responded to IL2 significantly higher than those from mice treated with IL2 alone or those from nontreated mice. Lymphocytes from mice treated with both cyclophosphamide and IL2 responded to IL2 almost same as normal lymphocytes. Cyclophosphamide treatment protected the appearance of both suppressor factor that were found in EL4-bearing mice and inhibited IL2 response of lymphocytes. These results suggested that combination therapy of cyclophosphamide and IL2 showed synergistic antitumor effect through the protection of IL2 responsiveness from suppression by suppressors. | |||||
| 書誌情報 |
群馬大学医療技術短期大学部紀要 巻 9, p. 169-179, 発行日 1989-03-31 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0389-7540 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00068340 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版者 | ||||||
| 出版者 | 群馬大学医療技術短期大学部 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Departmental Bulletin Paper | |||||
| 更新日 | ||||||
| 日付 | 2017-03-27 | |||||
| 日付タイプ | Created | |||||
