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ウサギ諸臓器・組織における蛋白質燐酸化酵素Cアイソザイムの免疫組織化学的研究
http://hdl.handle.net/10087/2043
http://hdl.handle.net/10087/20432a891d1c-7dc7-4776-8834-3c87a4c79fc6
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2007-12-20 | |||||
タイトル | ||||||
タイトル | ウサギ諸臓器・組織における蛋白質燐酸化酵素Cアイソザイムの免疫組織化学的研究 | |||||
言語 | ||||||
言語 | jpn | |||||
その他のタイトル | ||||||
その他のタイトル | Localization of Immunoreactive Protein Kinase C Isozymes in Normal Rabbit Tissues | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Protein kinase C isozymes | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Immunohistochemistry | |||||
著者 |
河原田, ウメ子
× 河原田, ウメ子× 福里, 利夫× 綿貫, 啓 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Immunoreactive protein kinase C (PKC) isozymes in normal rabbit tissues were immunohistochemically localized by the peroxidase anti-peroxidase complex method using monoclonal antibodies against rabbit brain PKC isozymes I, II, and III (PKC-I, II, and III). Immunoreactive PKC-I was present almost exclusively in the brain and PKC-II immunoreactivity was present predominantly in the lymphatic and reticuloendothelial systems. Definite staining for PKC-II isozyme was also found in chondrocytes of the cartilage and endocardial cells of the heart. Immunoreactive PKC-III-like molecules were distributed widely in many organs but more densely in particular portions or specific cells of the epithelial system as shown by intense staining in the pancreatic duct and macula densa of the renal tubuli. Differential distribution of the PKC isozymes in distinct cells or specific structures within each organ or tissue, such as PKC-II expression on the hepatic sinusoidal lining cells and PKC-III expression on the intrahepatic bile duct epithelium of the liver, was also indicated. These results provided new evidence for distinct patterns of tissue distribution and cellular or subcellular location of the isozymes of PKC in various tissues and suggested specific functions of each of the isoenzymes in the tissues and organs as well as the usefulness of immunohistochemical detection of PKC in a pathological study. | |||||
書誌情報 |
群馬大学医療技術短期大学部紀要 巻 14, p. 83-89, 発行日 1994-03-31 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0389-7540 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00068340 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
出版者 | ||||||
出版者 | 群馬大学医療技術短期大学部 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Departmental Bulletin Paper | |||||
更新日 | ||||||
日付 | 2017-03-27 | |||||
日付タイプ | Created |