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ESTABLISHMENT AND PARTIAL CHARACTERIZATION OF A NEW TUMORIGENIC EPITHELIAL-LIKE CELL LINE FROM RAT VENTRAL PROSTATE
http://hdl.handle.net/10087/2056
http://hdl.handle.net/10087/205672b58bad-095e-4067-8c5a-1e1aaf56b393
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00004436413.pdf (1.7 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-12-20 | |||||
| タイトル | ||||||
| タイトル | ESTABLISHMENT AND PARTIAL CHARACTERIZATION OF A NEW TUMORIGENIC EPITHELIAL-LIKE CELL LINE FROM RAT VENTRAL PROSTATE | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Cell line | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Rat ventral prostate | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Culture | |||||
| 著者 |
Ito, Yoshikazu Z.
× Ito, Yoshikazu Z.× Hiromachi, Sachiko× Futawatari, Tamae× Arai, Michiko× Nakazato, Yoichi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A tumorigenic epithelial-like cell line of rat prostate origin (PR4) was established in vitro. The cell line originated from a single cell of a previously established rat ventral prostate cell line, and has been serially subcultured more than 100 times over 5 years. The doubling time of the cells was 18 hours, and the saturation density was 5 x 10(6) cells/ml. Oval nuclei with dispersed chromatin and well developed cytoplasmic organelles were ultrastructural characteristics of the cells. The PR4 cells were transplanted into nude mice and the histology of the resulting tumors was neopolastic epithelial-like morphology that showed cells arranged in a sheet and cord structure with a solid pattern. Very high activities of prostatic acid phosphatase and beta-glucuronidase were observed in the cytosol of the cells. The PR4 cells did not respond to androgen. The use of the new cell line and other in vitro models of rat prostate as experimental tools for human prostatic cancer research was discussed. | |||||
| 書誌情報 |
群馬大学医療技術短期大学部紀要 巻 16, p. 99-107, 発行日 1996-03-31 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0389-7540 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00068340 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版者 | ||||||
| 出版者 | 群馬大学医療技術短期大学部 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Departmental Bulletin Paper | |||||
| 更新日 | ||||||
| 日付 | 2017-03-27 | |||||
| 日付タイプ | Created | |||||
