Duloxetine decreases locus coeruleus neuronal activity to restore stimuli-responsive activity, besides increases noradrenaline concentration in medial prefrontal cortex and spinal dorsal horn resulting in bidirectional effects on neuropathic pain in rats.

m-k2022-1

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m-k2022-1.pdf

https://gunma-u.repo.nii.ac.jp/record/2000775/files/m-k2022-1.pdf

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