@article{oai:gunma-u.repo.nii.ac.jp:00006121,
 author = {Hagiwara, Shuichi and Ogino, Takashi and Takahashi, Yuga and Isaka, Akira and Nameki, Taro and Kagoshima, Kaie and Yamada, Takuro and Ishihara, Kouichi and Hiraishi, Hikaru and Kurabayashi, Kazutaka and Handa, Hiroshi and Iino, Yuichi},
 issue = {4},
 journal = {The Kitakanto medical journal = 北関東医学},
 month = {Nov},
 note = {application/pdf, Journal Article, Tegafur/uracil (UFT) is an oral anticancer drug composed of tegafur which is a derivative of\nfluorouracil (5-FU) and uracil in a molar ratio of 1:4. UFT is effective as adjuvant chemotherapy for\nbreast cancer2, colorectal cancer3, non-small cell lung carcinoma4, head and neck cancer5 and other\ntumors. We report a 41-year-old man who orally ingested a large dose of UFT (tegafur: 40000 mg/\nuracil 9960mg)in an effort to commit suicide, and suffered from sub-acute toxicosis(main symptoms were\nbone-marrow suppression, and hair loss) of UFT. His life was saved by empiric antibiotic chemical\ntreatment (meropenem, isapamicin, and micafungin), and granulocyte colony-stimulating factor (G\n-CSF). In the case of toxicosis of UFT, strong antibacterial empiric chemotherapy and G-CSF are\nnecessary for rescue. If G-CSF is not work, biopsy of bone marrow woud be necessary, and the case of\nno stem cells, bone marrow transfusion should be thought.},
 pages = {317--320},
 title = {Sub-acute Toxicosis Caused by a Multiple Doses Tegafur/Uracil (UFT) for Suicide : A Case Report},
 volume = {57},
 year = {2007}
}