| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2011-08-25 |
| タイトル |
|
|
タイトル |
Lesions of supramammillary nucleus decreae self-grooming behavior of rats placed in an open field |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
supramammillary nucleus |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
lesion |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
open field |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
exploration |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
grooming |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Yamazaki, Chiho K.
Shirao, Tomoaki
Sasagawa, Yoshio
Maruyama, Yukio
Akita, Hisanao
Saji, Makoto
Sekino, Yuko
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Aim : Although subcortical regions send numerous efferent fibers to the hippocampus, their involvement\nin hippocampal functions has not been fu11y elucidated. The aim of this study was to determine the\nefTect of the supram ammillary nucleus (SuM) on the hippocampus. Methods : Neurons within the SuM\nof rats were destroyed by local injections of an excitotoxin, ibotenic acid, and the efTects of the\nSuM-lesion on behaviors in an open field were investigated. Results: SuM lesions increased distance\ntraveled, movement time and latency to start grooming, while they decreased time spent grooming. SuM\nlesions had no efTect on rearing frequency or immobility time. Conclusion : Prolonged exploration and\ndecrease in the total time spent grooming observed in the SuM-lesioned rats were consistent with the\nbeh avi oral characteri stics of hippocamp al -lesioned rats of the previ ous report s, suggesting that the SuM\nis involved in the establishment of spatial memory by hippocampus during the initial exploration of a\nnovel environment. In addition, the reduction of grooming in the SuM-lesioned animal suggests that\nSuM may be involved in emotion, such as anxiety. The results ofthis study show the involvement ofthe\nSuM in hippocampal function and in anxiety perceived in anovel environment. |
| 書誌情報 |
The Kitakanto medical journal = 北関東医学
巻 61,
号 3,
p. 287-292,
発行日 2011-08-01
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1343-2826 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN10585677 |
| フォーマット |
|
|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 |
|
|
出版者 |
北関東医学会 |
| 資源タイプ |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Journal Article |
| 更新日 |
|
|
日付 |
2017-03-27 |
|
日付タイプ |
Created |
61_287.pdf (252.4 kB)
