{"created":"2023-06-19T08:40:30.449413+00:00","id":7788,"links":{},"metadata":{"_buckets":{"deposit":"16443536-c22c-4c4b-9713-11489f6ec309"},"_deposit":{"created_by":2,"id":"7788","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"7788"},"status":"published"},"_oai":{"id":"oai:gunma-u.repo.nii.ac.jp:00007788","sets":["719:760:761:794"]},"author_link":["29451","29455","29452","29454","29458","29448","29446","29456","29449","29447","29450","29457","29453"],"item_6_alternative_title_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"A Study on recurrent gastrointestinal stromal tumor"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-08-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"232","bibliographicPageStart":"223","bibliographicVolumeNumber":"63","bibliographic_titles":[{"bibliographic_title":"The Kitakanto medical journal = 北関東医学"}]}]},"item_6_date_61":{"attribute_name":"更新日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2017-03-27","subitem_date_issued_type":"Created"}]},"item_6_description_39":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_6_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【背景と目的】原発 GISTに対する治療の第一選択は外科切除であるが ,再発症例に対する積極的治療が GISTの治療成績向上に繋がる.2008年に GIST診療ガイドラインが示されてから,再発症例に対する治療の原則はイマチニブの投与である .教室の再発 GIST症例を臨床病理学的に検討し治療法について検討した .【結果】男性 3例女性 4例の 7例で,平均年齢は 61.9歳であった.原発は胃 :1例,十二指腸 :1例,小腸 : 4例,直腸 :1例であった.リスク分類では中間 :2例,中間～高 :2例,高 :3例で,初再発は全例肝転移を伴い,再発までの期間は 14-77ヶ月であった.再発巣切除は 3例で,イマチニブ投与は 4例であった.7例中 5例が再再発または耐性になった.イマチニブを投与した 4例中 3例は耐性になり,1例はスニチニブに変更し 2例は局所耐性部を切除しイマチニブを継続した.7例中 2例死亡したが 5例は長期生存中である.【結語】 GIST再発ではイマチニブ投与が第一選択であるが,耐性になった場合,全身性の場合はスニチニブ投与 ,局所性では切除後イマチニブを継続投与するのがよい.","subitem_description_type":"Abstract"}]},"item_6_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"北関東医学会"}]},"item_6_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1343-2826","subitem_source_identifier_type":"ISSN"}]},"item_6_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10585677","subitem_source_identifier_type":"NCID"}]},"item_6_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"竹吉, 泉"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小川, 博臣"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"五十嵐, 隆通"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"塚越, 浩志"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"平井, 圭太郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"高橋, 憲史"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山崎, 穂高"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田中, 和美"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"高橋, 研吾"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"吉成, 大介"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"須納瀬, 豊"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岩崎, 茂"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"荒井, 剛"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-01-07"}],"displaytype":"detail","filename":"63_217.pdf","filesize":[{"value":"272.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"63_217.pdf","url":"https://gunma-u.repo.nii.ac.jp/record/7788/files/63_217.pdf"},"version_id":"8dee4368-bc1d-4dec-89e5-bfb310beddb7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"GIST(gastrointestinal stromal tumor)","subitem_subject_scheme":"Other"},{"subitem_subject":"再発","subitem_subject_scheme":"Other"},{"subitem_subject":"イマチニブ","subitem_subject_scheme":"Other"},{"subitem_subject":"スニチニブ","subitem_subject_scheme":"Other"},{"subitem_subject":"切除","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal 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