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Serum Apolipoprotein M Levels are Correlated with Biomarkers of Coagulation
http://hdl.handle.net/10087/9889
http://hdl.handle.net/10087/9889fec6e6a9-647c-4167-b5f8-ab50ce46c0b2
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
66_1.pdf (450.6 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-03-18 | |||||
| タイトル | ||||||
| タイトル | Serum Apolipoprotein M Levels are Correlated with Biomarkers of Coagulation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | apoliporpotein M | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | coagulation | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | activated partial thromboplastin time | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | prothrombin time | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Yoshida, Kensuke
× Yoshida, Kensuke× Kimura, Takao× Shimizu, Tomo× Sato, Koichi× Aoki, Tomoyuki× Sumino, Hiroyuki× Tsunekawa, Katsuhiko× Miyazaki, Osamu× Fukamachi, Isamu× Nakajima, Katsuyuki× Okajima, Fumikazu× Murakami, Masami |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background:Apolipoprotein M (ApoM) is bound to high-density lipoprotein (HDL) in plasma, and HDL hasanticoagulation effects. However, the association between ApoM and biomarkers of coagulation was unclear.Therefore, we investigated relationships between ApoM and biomarkers of coagulation.Methods: Serum samples from 233 Japanese participants including with diabetes mellitus, hypertension,dyslipidemia, or healthy controls were analyzed. Serum ApoM levels were measured using Enzyme-LinkedImmuno-Sorbent Assay(ELISA).Results:Analysis of all 233 participants showed that ApoM levels were positively correlated with age (r＝0.284,p＜0.001), total cholesterol (TC;r＝0.477, p＜0.001), HDL-cholesterol (HDL-C;r＝0.234, p＜0.001) and lowdensitylipoprotein cholesterol (LDL-C;r＝0.331, p＜0.001). Higher ApoM levels were correlated with shorteractivated partial thromboplastin time(APTT;r＝－0.226,p＝0.001) and prothrombin time(PT,％;r＝0.326,p＜0.001). Separate analysis of the 115 healthy controls showed that ApoM levels were positively correlated with age,TC, HDL-C and LDL-C, and higher ApoM levels were correlated with shorter PT.Conclusion:Serum levels of ApoM may influence biomarkers of coagulation. | |||||
| 書誌情報 |
The Kitakanto medical journal = 北関東医学 巻 66, 号 1, p. 1-6, 発行日 2016-02-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1343-2826 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN10585677 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | 北関東医学会 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal Article | |||||
| 更新日 | ||||||
| 日付 | 2017-03-27 | |||||
| 日付タイプ | Created | |||||
