| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2016-03-18 |
| タイトル |
|
|
タイトル |
Serum Apolipoprotein M Levels are Correlated with Biomarkers of Coagulation |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
apoliporpotein M |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
coagulation |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
activated partial thromboplastin time |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
prothrombin time |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Yoshida, Kensuke
Kimura, Takao
Shimizu, Tomo
Sato, Koichi
Aoki, Tomoyuki
Sumino, Hiroyuki
Tsunekawa, Katsuhiko
Miyazaki, Osamu
Fukamachi, Isamu
Nakajima, Katsuyuki
Okajima, Fumikazu
Murakami, Masami
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background:Apolipoprotein M (ApoM) is bound to high-density lipoprotein (HDL) in plasma, and HDL hasanticoagulation effects. However, the association between ApoM and biomarkers of coagulation was unclear.Therefore, we investigated relationships between ApoM and biomarkers of coagulation.Methods: Serum samples from 233 Japanese participants including with diabetes mellitus, hypertension,dyslipidemia, or healthy controls were analyzed. Serum ApoM levels were measured using Enzyme-LinkedImmuno-Sorbent Assay(ELISA).Results:Analysis of all 233 participants showed that ApoM levels were positively correlated with age (r＝0.284,p＜0.001), total cholesterol (TC;r＝0.477, p＜0.001), HDL-cholesterol (HDL-C;r＝0.234, p＜0.001) and lowdensitylipoprotein cholesterol (LDL-C;r＝0.331, p＜0.001). Higher ApoM levels were correlated with shorteractivated partial thromboplastin time(APTT;r＝－0.226,p＝0.001) and prothrombin time(PT,％;r＝0.326,p＜0.001). Separate analysis of the 115 healthy controls showed that ApoM levels were positively correlated with age,TC, HDL-C and LDL-C, and higher ApoM levels were correlated with shorter PT.Conclusion:Serum levels of ApoM may influence biomarkers of coagulation. |
| 書誌情報 |
The Kitakanto medical journal = 北関東医学
巻 66,
号 1,
p. 1-6,
発行日 2016-02-01
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1343-2826 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN10585677 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 |
|
|
出版者 |
北関東医学会 |
| 資源タイプ |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Journal Article |
| 更新日 |
|
|
日付 |
2017-03-27 |
|
日付タイプ |
Created |
66_1.pdf (450.6 kB)
