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  1. 30 医学系研究科
  2. 3005 北関東医学会
  3. 330501 The Kitakanto medical journal
  4. Vol.69 No.3(2019)

Child-Pugh Classification using Magnetic Resonance Imaging using Gadoxetic Acid-based Contrast Agent Compared with Indocyanine Green and 99mTc-galactosyl-human Serum Albumin Liver Scintigraphy

http://hdl.handle.net/10087/00014036
http://hdl.handle.net/10087/00014036
cc268246-b532-4651-bc0a-6c1ef9878962
名前 / ファイル ライセンス アクション
69_183.pdf 69_183.pdf (934.6 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2023-03-23
タイトル
タイトル Child-Pugh Classification using Magnetic Resonance Imaging using Gadoxetic Acid-based Contrast Agent Compared with Indocyanine Green and 99mTc-galactosyl-human Serum Albumin Liver Scintigraphy
言語
言語 eng
キーワード
主題Scheme Other
主題 Child-Pugh classification
キーワード
主題Scheme Other
主題 EOB
キーワード
主題Scheme Other
主題 MRI
キーワード
主題Scheme Other
主題 Liver function
キーワード
主題Scheme Other
主題 Hepatobiliary phase
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Manduul, Enkhjargal

× Manduul, Enkhjargal

40049

Manduul, Enkhjargal

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Nakajima, Takahito

× Nakajima, Takahito

40050

Nakajima, Takahito

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Shibuya, Kei

× Shibuya, Kei

40051

Shibuya, Kei

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Shrestha, Suman

× Shrestha, Suman

40052

Shrestha, Suman

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Hirasawa, Hiromi

× Hirasawa, Hiromi

40053

Hirasawa, Hiromi

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Tsushima, Yoshito

× Tsushima, Yoshito

40054

Tsushima, Yoshito

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抄録
内容記述タイプ Abstract
内容記述 This study evaluated liver function using gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) to improve assessment of patients with liver tumors compared to Child-Pugh classification (CPC). Materials and methods: The liver function of 59 patients was assessed to determine the indication for heavy ion therapy. Clinical and laboratory assessments, including 99mTc-GSA liver scintigraphy and indocyanine green retention index (ICGR15), were performed for liver function assessment. EOB-MRI was performed on T1W1 images both before and after Gd-EOB-DTPA administration and hepatobiliary phase images were acquired 20-min post-injection. Liver parenchymal enhancement ratio (LER) was measured based on liver-to-spleen (L/Sp) ratios calculating the average liver intensity divided by spleen intensity. Results: The mean LER values on MRI were 138.2±12.8 (133.9-142.5), 115.7±11.6 (110.0-121.5), and 93.2±15.8 (73.6-112.9) in CPC-A, -B and -C, respectively. From the correlation between the LER on MRI and ICGR15 and parameters of 99mTc-GSA liver scintigraphy, LER on MRI was highly significantly correlated with ICGR15 (r=-0.67; p<0.0001). Discussion: This study demonstrated that LER values on EOB-MRI could classify liver function and had high correlation with CPC and ICGR15.
書誌情報 The Kitakanto medical journal = 北関東医学

巻 69, 号 3, p. 183-189, 発行日 2019-08-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 1343-2826
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN10585677
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
出版者
出版者 北関東医学会
資源タイプ
内容記述タイプ Other
内容記述 Journal Article
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