Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2023-03-23 |
タイトル |
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タイトル |
Child-Pugh Classification using Magnetic Resonance Imaging using Gadoxetic Acid-based Contrast Agent Compared with Indocyanine Green and 99mTc-galactosyl-human Serum Albumin Liver Scintigraphy |
言語 |
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言語 |
eng |
キーワード |
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主題Scheme |
Other |
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主題 |
Child-Pugh classification |
キーワード |
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主題Scheme |
Other |
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主題 |
EOB |
キーワード |
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主題Scheme |
Other |
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主題 |
MRI |
キーワード |
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主題Scheme |
Other |
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主題 |
Liver function |
キーワード |
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主題Scheme |
Other |
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主題 |
Hepatobiliary phase |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
著者 |
Manduul, Enkhjargal
Nakajima, Takahito
Shibuya, Kei
Shrestha, Suman
Hirasawa, Hiromi
Tsushima, Yoshito
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抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
This study evaluated liver function using gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) to improve assessment of patients with liver tumors compared to Child-Pugh classification (CPC). Materials and methods: The liver function of 59 patients was assessed to determine the indication for heavy ion therapy. Clinical and laboratory assessments, including 99mTc-GSA liver scintigraphy and indocyanine green retention index (ICGR15), were performed for liver function assessment. EOB-MRI was performed on T1W1 images both before and after Gd-EOB-DTPA administration and hepatobiliary phase images were acquired 20-min post-injection. Liver parenchymal enhancement ratio (LER) was measured based on liver-to-spleen (L/Sp) ratios calculating the average liver intensity divided by spleen intensity. Results: The mean LER values on MRI were 138.2±12.8 (133.9-142.5), 115.7±11.6 (110.0-121.5), and 93.2±15.8 (73.6-112.9) in CPC-A, -B and -C, respectively. From the correlation between the LER on MRI and ICGR15 and parameters of 99mTc-GSA liver scintigraphy, LER on MRI was highly significantly correlated with ICGR15 (r=-0.67; p<0.0001). Discussion: This study demonstrated that LER values on EOB-MRI could classify liver function and had high correlation with CPC and ICGR15. |
書誌情報 |
The Kitakanto medical journal = 北関東医学
巻 69,
号 3,
p. 183-189,
発行日 2019-08-01
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ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1343-2826 |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AN10585677 |
著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
出版者 |
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出版者 |
北関東医学会 |
資源タイプ |
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内容記述タイプ |
Other |
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内容記述 |
Journal Article |