{"created":"2023-06-19T08:42:13.908603+00:00","id":9865,"links":{},"metadata":{"_buckets":{"deposit":"feb07ae5-7182-421d-ab24-2e04b2439e2f"},"_deposit":{"created_by":2,"id":"9865","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"9865"},"status":"published"},"_oai":{"id":"oai:gunma-u.repo.nii.ac.jp:00009865","sets":["719:760:761:865"]},"author_link":["40475","40474"],"item_6_alternative_title_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Multiple Myeloma: Current Advances and Future Directions"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-08-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"185","bibliographicPageStart":"175","bibliographicVolumeNumber":"70","bibliographic_titles":[{"bibliographic_title":"The Kitakanto medical journal = 北関東医学"}]}]},"item_6_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Murakami, Hirokazu"}],"nameIdentifiers":[{}]}]},"item_6_description_39":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_6_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"これまで，多発性骨髄腫の予後は極めて不良で治癒は困難とされていた．しかし，近年サリドマイドなどの免疫調整薬，ボルテゾミブなどのプロテアソーム阻害薬，さらにダラツムマブなどの抗体薬を含めた新規薬剤の導入により治療成績は著しく向上し，生存曲線にプラトーが得られるようになってきた．また，微小残存病変の検出法も進歩し，治療効果の判定の精度も向上したため，的確な治療戦略が組めるようになった．今後，CAR-T療法をはじめとした強力な免疫療法の導入も想定され，治癒が望めると言っても過言ではない．","subitem_description_type":"Abstract"}]},"item_6_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"北関東医学会"}]},"item_6_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1343-2826","subitem_source_identifier_type":"ISSN"}]},"item_6_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10585677","subitem_source_identifier_type":"NCID"}]},"item_6_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"村上, 博和"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-03-23"}],"displaytype":"detail","filename":"70_175.pdf","filesize":[{"value":"852.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"70_175.pdf","url":"https://gunma-u.repo.nii.ac.jp/record/9865/files/70_175.pdf"},"version_id":"99c17d43-f100-479a-a43d-24283e8f7083"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"多発性骨髄腫","subitem_subject_scheme":"Other"},{"subitem_subject":"International Myeloma Working group","subitem_subject_scheme":"Other"},{"subitem_subject":"International Staging System","subitem_subject_scheme":"Other"},{"subitem_subject":"新規薬剤","subitem_subject_scheme":"Other"},{"subitem_subject":"微小残存病変","subitem_subject_scheme":"Other"},{"subitem_subject":"multiple myeloma","subitem_subject_scheme":"Other"},{"subitem_subject":"novel agent","subitem_subject_scheme":"Other"},{"subitem_subject":"minimal residual disease","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"多発性骨髄腫診療の進歩と将来","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"多発性骨髄腫診療の進歩と将来"},{"subitem_title":"Multiple Myeloma: Current Advances and Future Directions","subitem_title_language":"en"}]},"item_type_id":"6","owner":"2","path":["865"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-03-23"},"publish_date":"2023-03-23","publish_status":"0","recid":"9865","relation_version_is_last":true,"title":["多発性骨髄腫診療の進歩と将来"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-06-19T09:51:16.128700+00:00"}