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The NP-2 cell system for analyses of the coreceptor usage of human and simian immunodeficiency viruses
http://hdl.handle.net/10087/6684
http://hdl.handle.net/10087/6684a2be486f-2a5f-4883-b522-d7f742d5bf01
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
62_1.pdf (1.9 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2012-03-02 | |||||
| タイトル | ||||||
| タイトル | The NP-2 cell system for analyses of the coreceptor usage of human and simian immunodeficiency viruses | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | HIV-1 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | CD4 receptor | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | coreceptor use | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | AIDS | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Hoshino, Hiroo
× Hoshino, Hiroo |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-\n2) are the causative agents of acquired immune deficiency syndrome.\nOur interests have focused on HIV entry into target cells and HIV cell\ntropism. The cell tropi sm of HIV and the det erm inants of a cell's\nsusceptibility to HIV infection have been mainly explained by the\ncombination of HIV surface proteins, Env, and expression ofCD4 and\ncoreceptors on the target cells. The coreceptors are molecules belong-\ning to the G prot ein-coupled 7-transm embrane receptors, esp ecially\nchemokine receptors. We propose that many researchers working in\nthis fi eld have noticed that our sy st em of using a human glioma cell\nline, NP-2, has be en quite use fu1 for the id entification of HIV corec e-\nptors, for the det erm in ation of coreceptor usage in HIV strains and for\nthe isolation of primary HIV-1 strains, and for the titration of in-\nfectivity. The properties of the assay systems using NP-2 cells that we\nhave developed are summarized in this review through an introduction\nof some of our wotk. | |||||
| 書誌情報 |
The Kitakanto medical journal = 北関東医学 巻 62, 号 1, p. 1-14, 発行日 2012-02-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1343-2826 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN10585677 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | 北関東医学会 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal Article | |||||
| 更新日 | ||||||
| 日付 | 2017-03-27 | |||||
| 日付タイプ | Created | |||||
