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Positron Emission Tomography/Computed Tomography before Treatment as a Predictor of 90Y-Ibritumomab Tiuxetan Response
http://hdl.handle.net/10087/12770
http://hdl.handle.net/10087/1277032c5c59e-d6f1-4b4a-9a1a-d09af4430863
名前 / ファイル | ライセンス | アクション |
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68_151.pdf (459.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-12-03 | |||||
タイトル | ||||||
タイトル | Positron Emission Tomography/Computed Tomography before Treatment as a Predictor of 90Y-Ibritumomab Tiuxetan Response | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | non-Hodgkin lymphoma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | radioimmunotherapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 90Y-Ibritumomab tiuxetan | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | FDG-PET╱CT | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | response predictor | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yudistiro, Ryan
× Yudistiro, Ryan× Heryanto, Yusri Dwi× Kodaira, Sayaka× Higuchi, Tetsuya× Arisaka, Yukiko× Tokue, Azusa× Taketomi-Takahashi, Ayako× Tsukamoto, Norifumi× Yokohama, Akihiko× Handa, Hiroshi× Koiso, Hiromi× Ishizaki, Takuma× Tsushima, Yoshiko |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background and Aims: Radioimmunotherapy (RIT) appears as one of the most effective treatment options for patientswith relapsed or resistant non-Hodgkin’s lymphoma (NHL). Our aim was to evaluate the role of pre-RIT 18F-fluorodeoxyglucose-positron emission tomography╱computed tomography (FDG-PET╱CT) as an early predictor of 90Y-Ibritumomabtiuxetan treatment response. Methods: We included consecutive 20 patients with relapsed NHL (10 males; meanage, 58.5 ± 8.9 years old) who were treated with 90Y-Ibritumomab tiuxetan. FDG-PET╱CT was performed before andafter treatment. Semiquantitative parameters of all measurable FDG-avid lesions were measured and averaged. Ameasurable FDG-avid lesion was defined as a lesion that showed FDG uptake higher than liver with a diameter morethan 1 cm. Treatment response was determined by visual assessment based on a five-point score criteria from FDGPET╱CT after treatment. Results: Fourteen patients (70%) were classified as responders and the other six patients(30%) as non-responders. All semiquantitative parameters except for MTV demonstrated significantly lower values inthe responders compared with the non-responders (p<0.05). Conclusions: Semiquantitative evaluation by SUVmax,SUVpeak, and TLG before treatment were useful as early predictors of 90Y-Ibritumomab tiuxetan treatment response. | |||||
書誌情報 |
The Kitakanto medical journal = 北関東医学 巻 68, 号 3, p. 151-156, 発行日 2018-08-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1343-2826 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10585677 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 北関東医学会 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article | |||||
更新日 | ||||||
日付 | 2019-12-04 | |||||
日付タイプ | Created |