WEKO3
アイテム
{"_buckets": {"deposit": "fa821ee9-5a15-4543-97c1-47498c06f8c7"}, "_deposit": {"created_by": 2, "id": "7984", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "7984"}, "status": "published"}, "_oai": {"id": "oai:gunma-u.repo.nii.ac.jp:00007984", "sets": ["796"]}, "author_link": ["30715", "30716", "30717", "30714", "30725", "30727", "30711", "30712", "30732", "30726", "30720", "30719", "30722", "30718", "30729", "30733", "30728", "30709", "30723", "30708", "30724", "30710", "30721", "30731", "30713", "30730"], "item_6_alternative_title_18": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "A Newly Diagnosed CML-CP HBV Carrier was Safely Treated with Dasatinib and Entecavir"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2014-02-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "55", "bibliographicPageStart": "51", "bibliographicVolumeNumber": "64", "bibliographic_titles": [{"bibliographic_title": "The Kitakanto medical journal = 北関東医学"}]}]}, "item_6_creator_3": {"attribute_name": "著者別名", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Takei, Hisashi"}], "nameIdentifiers": [{"nameIdentifier": "30721", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mitsui, Takeki"}], "nameIdentifiers": [{"nameIdentifier": "30722", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato, Naru"}], "nameIdentifiers": [{"nameIdentifier": "30723", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saito, Akio"}], "nameIdentifiers": [{"nameIdentifier": "30724", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hoshino, Takumi"}], "nameIdentifiers": [{"nameIdentifier": "30725", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Koiso, Hiromi"}], "nameIdentifiers": [{"nameIdentifier": "30726", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takizawa, Makiko"}], "nameIdentifiers": [{"nameIdentifier": "30727", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yokohama, Akihiko"}], "nameIdentifiers": [{"nameIdentifier": "30728", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saito, Takayuki"}], "nameIdentifiers": [{"nameIdentifier": "30729", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tsukamoto, Norifumi"}], "nameIdentifiers": [{"nameIdentifier": "30730", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Murakami, Hirokazu"}], "nameIdentifiers": [{"nameIdentifier": "30731", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Handa, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "30732", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nojima, Yoshihisa"}], "nameIdentifiers": [{"nameIdentifier": "30733", "nameIdentifierScheme": "WEKO"}]}]}, "item_6_date_61": {"attribute_name": "更新日", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2017-03-27", "subitem_date_issued_type": "Created"}]}, "item_6_description_39": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"subitem_description": "Journal Article", "subitem_description_type": "Other"}]}, "item_6_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "症例は63歳男性. 血液検査, 骨髄検査から慢性骨髄性白血病慢性期(CML-CP) と診断した. 初診時よりHBV-DNA が検出され,HBVキャリアと診断した.チロシンキナーゼ阻害薬(TKI)投与によるHBV再活性化の可能性を考慮しentecavir 0.5mg/日の投与を先行した. HBV-DNA 量の低下を確認しdasatinib 100mg/日の併用を開始した. 投与3ヵ月後に細胞遺伝学的部分寛解, 12ヶ月後に分子生物学的大寛解を得た. 治療経過中HBV再活性化, 肝障害は認めず, 現在も併用療法継続中である. 近年, 免疫抑制作用を持つ薬剤によるHBV再活性化が報告されている. Dasatinibも免疫抑制作用を持つと考えられており, HBV再活性化の可能性が示唆される.HBVキャリアCML-CPに対し,entecavirとdasatinibを併用し安全に治療を継続し得た症例を経験したので報告する.", "subitem_description_type": "Abstract"}]}, "item_6_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "北関東医学会"}]}, "item_6_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1343-2826", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_9": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN10585677", "subitem_source_identifier_type": "NCID"}]}, "item_6_version_type_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "武井, 寿史"}], "nameIdentifiers": [{"nameIdentifier": "30708", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "三井, 健揮"}], "nameIdentifiers": [{"nameIdentifier": "30709", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "佐藤, 成"}], "nameIdentifiers": [{"nameIdentifier": "30710", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "斉藤, 明生"}], "nameIdentifiers": [{"nameIdentifier": "30711", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "星野, 匠臣"}], "nameIdentifiers": [{"nameIdentifier": "30712", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "小磯, 博美"}], "nameIdentifiers": [{"nameIdentifier": "30713", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "滝沢, 牧子"}], "nameIdentifiers": [{"nameIdentifier": "30714", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "横濱, 章彦"}], "nameIdentifiers": [{"nameIdentifier": "30715", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "斉藤, 貴之"}], "nameIdentifiers": [{"nameIdentifier": "30716", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "塚本, 憲史"}], "nameIdentifiers": [{"nameIdentifier": "30717", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "村上, 博和"}], "nameIdentifiers": [{"nameIdentifier": "30718", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "半田, 寛"}], "nameIdentifiers": [{"nameIdentifier": "30719", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "野島, 美久"}], "nameIdentifiers": [{"nameIdentifier": "30720", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2021-01-07"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "64_51.pdf", "filesize": [{"value": "302.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 302700.0, "url": {"label": "64_51.pdf", "url": "https://gunma-u.repo.nii.ac.jp/record/7984/files/64_51.pdf"}, "version_id": "e3077a22-7207-4172-8ac1-def74a83df1e"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "HBVキャリア", "subitem_subject_scheme": "Other"}, {"subitem_subject": "慢性骨髄性白血病", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ダサチニブ", "subitem_subject_scheme": "Other"}, {"subitem_subject": "エンテカビル", "subitem_subject_scheme": "Other"}, {"subitem_subject": "HBV再活性化", "subitem_subject_scheme": "Other"}, {"subitem_subject": "hapatitis B virus (HBV) carrier", "subitem_subject_scheme": "Other"}, {"subitem_subject": "chronic myedoid leukemia (CML)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "dasatinib", "subitem_subject_scheme": "Other"}, {"subitem_subject": "entecavir", "subitem_subject_scheme": "Other"}, {"subitem_subject": "HBV reactivation", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Entecavirとdasatinibを併用し,安全に治療継続し得たHBVキャリアの新規発症慢性骨髄性白血病慢性期", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Entecavirとdasatinibを併用し,安全に治療継続し得たHBVキャリアの新規発症慢性骨髄性白血病慢性期"}, {"subitem_title": "A Newly Diagnosed CML-CP HBV Carrier was Safely Treated with Dasatinib and Entecavir", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "2", "path": ["796"], "permalink_uri": "http://hdl.handle.net/10087/8133", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-02-27"}, "publish_date": "2014-02-27", "publish_status": "0", "recid": "7984", "relation": {}, "relation_version_is_last": true, "title": ["Entecavirとdasatinibを併用し,安全に治療継続し得たHBVキャリアの新規発症慢性骨髄性白血病慢性期"], "weko_shared_id": -1}
Entecavirとdasatinibを併用し,安全に治療継続し得たHBVキャリアの新規発症慢性骨髄性白血病慢性期
http://hdl.handle.net/10087/8133
http://hdl.handle.net/10087/81330a870ed5-71d4-4a39-bf00-a1295bc1d312
名前 / ファイル | ライセンス | アクション |
---|---|---|
64_51.pdf (302.7 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2014-02-27 | |||||
タイトル | ||||||
タイトル | Entecavirとdasatinibを併用し,安全に治療継続し得たHBVキャリアの新規発症慢性骨髄性白血病慢性期 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | A Newly Diagnosed CML-CP HBV Carrier was Safely Treated with Dasatinib and Entecavir | |||||
言語 | ||||||
言語 | jpn | |||||
その他のタイトル | ||||||
その他のタイトル | A Newly Diagnosed CML-CP HBV Carrier was Safely Treated with Dasatinib and Entecavir | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HBVキャリア | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 慢性骨髄性白血病 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ダサチニブ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | エンテカビル | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HBV再活性化 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hapatitis B virus (HBV) carrier | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | chronic myedoid leukemia (CML) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | dasatinib | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | entecavir | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HBV reactivation | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
武井, 寿史
× 武井, 寿史× 三井, 健揮× 佐藤, 成× 斉藤, 明生× 星野, 匠臣× 小磯, 博美× 滝沢, 牧子× 横濱, 章彦× 斉藤, 貴之× 塚本, 憲史× 村上, 博和× 半田, 寛× 野島, 美久 |
|||||
著者別名 |
Takei, Hisashi
× Takei, Hisashi× Mitsui, Takeki× Sato, Naru× Saito, Akio× Hoshino, Takumi× Koiso, Hiromi× Takizawa, Makiko× Yokohama, Akihiko× Saito, Takayuki× Tsukamoto, Norifumi× Murakami, Hirokazu× Handa, Hiroshi× Nojima, Yoshihisa |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 症例は63歳男性. 血液検査, 骨髄検査から慢性骨髄性白血病慢性期(CML-CP) と診断した. 初診時よりHBV-DNA が検出され,HBVキャリアと診断した.チロシンキナーゼ阻害薬(TKI)投与によるHBV再活性化の可能性を考慮しentecavir 0.5mg/日の投与を先行した. HBV-DNA 量の低下を確認しdasatinib 100mg/日の併用を開始した. 投与3ヵ月後に細胞遺伝学的部分寛解, 12ヶ月後に分子生物学的大寛解を得た. 治療経過中HBV再活性化, 肝障害は認めず, 現在も併用療法継続中である. 近年, 免疫抑制作用を持つ薬剤によるHBV再活性化が報告されている. Dasatinibも免疫抑制作用を持つと考えられており, HBV再活性化の可能性が示唆される.HBVキャリアCML-CPに対し,entecavirとdasatinibを併用し安全に治療を継続し得た症例を経験したので報告する. | |||||
書誌情報 |
The Kitakanto medical journal = 北関東医学 巻 64, 号 1, p. 51-55, 発行日 2014-02-01 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1343-2826 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10585677 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 北関東医学会 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article | |||||
更新日 | ||||||
日付 | 2017-03-27 | |||||
日付タイプ | Created |